Mathematical models of cell cycle regulation

نویسندگان

  • Hendrik Fuß
  • Werner Dubitzky
  • C. Stephen Downes
  • Mary Jo Kurth
چکیده

The cell division cycle is a fundamental process of cell biology and a detailed understanding of its function, regulation and other underlying mechanisms is critical to many applications in biotechnology and medicine. Since a comprehensive analysis of the molecular mechanisms involved is too complex to be performed intuitively, mathematical and computational modelling techniques are essential. This paper is a review and analysis of recent approaches attempting to model cell cycle regulation by means of protein-protein interaction networks.

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عنوان ژورنال:
  • Briefings in bioinformatics

دوره 6 2  شماره 

صفحات  -

تاریخ انتشار 2005